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CD45RA [111-1C5]
Product group: | Primary |
Monoclonal/ Polyclonal: | Monoclonal |
Clone: | 111-1C5 |
Host: | Mouse |
Isotype: | IgG1 |
Application: | Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC) |
Application notes: | 50-200 |
Conjugation Type: | Unconjugated |
Lightchain type: | Kappa |
Reactivity: | Human |
General notes: | Localization: membrane. |
Buffer: | citrate pH6.0 |
UNSPSC code: | 12352203 |
CD45 or Leukocyte Common Antigen (LCA/T200) belongs to a family of membrane sialoglycoproteins with MW of 180kDa-220kDa. Human CD45 contains three exons which encode peptidesegments designated A, B and C, respectively. The differential splicing of the exons generates various isoforms. CD45RA.is a single chain glycoprotein. It is expressed on appoximately 40-50% of peripheral CD4+ T-cells, 50% of peripheral CD8+ T-cells, B-cells, and leukemic B-cell lines. T-cells expressing CD45RA and CD45RO define complementary, predominantly non-overlapping populations of resting peripheral T-cells. CD45RA are naive orvirgin T-cells while, T-cells expressing CD45RO are memory T-cells. (Shipping Cost: €200.00)
CD45RA [111-1C5]
CD45 or Leukocyte Common Antigen (LCA/T200) belongs to a family of membrane sialoglycoproteins with MW of 180kDa-220kDa. Human CD45 contains three exons which encode peptidesegments designated A, B and C, respectively. The differential splicing of the exons generates various isoforms. CD45RA.is a single chain glycoprotein. It is expressed on appoximately 40-50% of peripheral CD4+ T-cells, 50% of peripheral CD8+ T-cells, B-cells, and leukemic B-cell lines. T-cells expressing CD45RA and CD45RO define complementary, predominantly non-overlapping populations of resting peripheral T-cells. CD45RA are naive orvirgin T-cells while, T-cells expressing CD45RO are memory T-cells.
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