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CD147/EMMPRIN/Neurothelin [8D6]
Product group: | Primary |
Monoclonal/ Polyclonal: | Monoclonal |
Clone: | 8D6 |
Host: | Mouse |
Isotype: | IgG1 |
Application: | Flow cytometry (FC), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) |
Application notes: | 50-200 |
Conjugation Type: | Unconjugated |
Reactivity: | Human |
General notes: | Localization: membrane. |
Buffer: | citrate pH6.0 |
UNSPSC code: | 12352203 |
This antibody recognizes extracellular epitope 2 within the N-terminal Ig domain of human CD147. It is expressed more intensely on thymocytes than on mature peripheral blood T cells. CD147 is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. It stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes are important factors in cancer invasion and metastasis. (Shipping Cost: €200.00)
CD147/EMMPRIN/Neurothelin [8D6]
This antibody recognizes extracellular epitope 2 within the N-terminal Ig domain of human CD147. It is expressed more intensely on thymocytes than on mature peripheral blood T cells. CD147 is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. It stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes are important factors in cancer invasion and metastasis.
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