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CD117/c-Kit [EPR22566-344]

Product information References Bioinformatics Documents
Product group: Primary
Monoclonal/ Polyclonal: Monoclonal
Clone: EP10
Host: Rabbit
Isotype: IgG
Application: Immunohistochemistry (IHC)
Application notes: 50-200
Conjugation Type: Unconjugated
Reactivity: Human
General notes: Localization: membrane, cytoplasm.
Buffer: citrate pH6.0 or EDTA pH8.0
UNSPSC code: 12352203

Member of the Tyrosine Kinase Receptor (TKRs) and highly homologous to receptor PDF and CSF-1. Activation of c-Kit tyrosine kinase by SCF (Stem Cell factor) leads to autophosphorylation and association of c-Kit with substrate PI3K. CD117 is a marker for Mast cell and gastrointerstinal stroma tumor. This anti-CD117 has been validated with excellent staining result by NordiQC, an independent scientific organization, promoting the quality of immunohistochemistry for pathology laboratories. (Shipping Cost: €200.00)

CD117/c-Kit [EP10]

Member of the Tyrosine Kinase Receptor (TKRs) and highly homologous to receptor PDF and CSF-1. Activation of c-Kit tyrosine kinase by SCF (Stem Cell factor) leads to autophosphorylation and association of c-Kit with substrate PI3K. CD117 is a marker for Mast cell and gastrointerstinal stroma tumor. This anti-CD117 has been validated with excellent staining result by NordiQC, an independent scientific organization, promoting the quality of immunohistochemistry for pathology laboratories.