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CD117/c-Kit [C117/370]
Product group: | Primary |
Monoclonal/ Polyclonal: | Monoclonal |
Clone: | C117/370 |
Host: | Mouse |
Isotype: | IgG1 |
Application: | Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC) |
Application notes: | 50-200 |
Conjugation Type: | Unconjugated |
Lightchain type: | Kappa |
Reactivity: | Human |
General notes: | Localization: membrane, cytoplasm. |
Buffer: | Tris EDTA pH9.0 |
UNSPSC code: | 12352203 |
Member of the Tyrosine Kinase Receptor (TKRs) and highly homologous to receptor PDF and CSF-1. Activation of c-Kit tyrosine kinase by SCF (Stem Cell factor) leads to autophosphorylation and association of c-Kit with substrate PI3K. CD117 is a marker for Mast cell and gastrointerstinal stroma tumor. This anti-CD117 has been validated with excellent staining result by NordiQC, an independent scientific organization, promoting the quality of immunohistochemistry for pathology laboratories. (Shipping Cost: €200.00)
CD117/c-Kit [C117/370]
Member of the Tyrosine Kinase Receptor (TKRs) and highly homologous to receptor PDF and CSF-1. Activation of c-Kit tyrosine kinase by SCF (Stem Cell factor) leads to autophosphorylation and association of c-Kit with substrate PI3K. CD117 is a marker for Mast cell and gastrointerstinal stroma tumor. This anti-CD117 has been validated with excellent staining result by NordiQC, an independent scientific organization, promoting the quality of immunohistochemistry for pathology laboratories.
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