CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.

You are here

Products

Products

back to search results

CD103/Integrin alpha E [ITGAE/2063]

Product information References Bioinformatics Documents
Product group: Primary
Monoclonal/ Polyclonal: Monoclonal
Clone: ITGAE/2063
Host: Mouse
Isotype: IgG2c
Application: Immunohistochemistry (IHC)
Application notes: 50-200
Conjugation Type: Unconjugated
Lightchain type: Kappa
Reactivity: Human
General notes: Localization: membrane, cytoplasm.
Buffer: citrate pH6.0
UNSPSC code: 12352203

CD103, also known as integrin alpha E (ITGAE), is an integrin protein that in humans is encoded by the ITGAE gene. It binds integrin beta 7 to form the complete heterodimeric molecular αEβ7 that binds to an extracellular matrix component and cellular counter receptor. They mediate cell adhesion, migration and signaling and are important for T lymphocyte localization. CD103 is expressed on intraepithelial lymphocytes in mucosal areas, including lung and GI tract. In malignancies, CD103 is present on all enteropathy-type T-cell lymphomas. Additionally, CD103 has been a useful marker for hairy cell leukemia. (Shipping Cost: €200.00)

CD103/Integrin alpha E [ITGAE/2063]

CD103, also known as integrin alpha E (ITGAE), is an integrin protein that in humans is encoded by the ITGAE gene. It binds integrin beta 7 to form the complete heterodimeric molecular αEβ7 that binds to an extracellular matrix component and cellular counter receptor. They mediate cell adhesion, migration and signaling and are important for T lymphocyte localization. CD103 is expressed on intraepithelial lymphocytes in mucosal areas, including lung and GI tract. In malignancies, CD103 is present on all enteropathy-type T-cell lymphomas. Additionally, CD103 has been a useful marker for hairy cell leukemia.