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Cadherin-K/CDH6 [MD129R]
| Product group: | Primary |
| Monoclonal/ Polyclonal: | Monoclonal |
| Clone: | EP217 |
| Host: | Rabbit |
| Isotype: | IgG |
| Application: | Immunohistochemistry (IHC) |
| Application notes: | Prediluted |
| Conjugation Type: | Unconjugated |
| Reactivity: | Human |
| General notes: | Localization: membrane. |
| Buffer: | EDTA pH8.0 |
| UNSPSC code: | 12352203 |
Cadherin-6 is a member of the cadherin superfamily. Cadherins are membrane glycoproteins that mediate homophilic cell-cell adhesion and play critical roles in cell differentiation and morphogenesis. It is a type II cadherin and may play a role in kidney development as well as endometrium and placenta formation. Cadherin-6 is highly expressed in kidney and the central nervous system. It has been found to be related to fetal kidney development and has been identified as a major cadherin in renal proximal tubules where conventional renal cell carcinoma originates. The expression of Cadherin-6 is associated with tumor progression in renal cell carcinoma. (Shipping Cost: €200.00)
Cadherin-6/Cadherin-K/CDH6 [EP217]
Cadherin-6 is a member of the cadherin superfamily. Cadherins are membrane glycoproteins that mediate homophilic cell-cell adhesion and play critical roles in cell differentiation and morphogenesis. It is a type II cadherin and may play a role in kidney development as well as endometrium and placenta formation. Cadherin-6 is highly expressed in kidney and the central nervous system. It has been found to be related to fetal kidney development and has been identified as a major cadherin in renal proximal tubules where conventional renal cell carcinoma originates. The expression of Cadherin-6 is associated with tumor progression in renal cell carcinoma.
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