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Cadherin-E/CD324 [MD128R]

Product information References Bioinformatics Documents
Product group: Primary
Monoclonal/ Polyclonal: Monoclonal
Clone: EP6
Host: Rabbit
Isotype: IgG
Application: Immunohistochemistry (IHC)
Application notes: 50-200
Conjugation Type: Unconjugated
Reactivity: Human
General notes: Localization: membrane.
Buffer: citrate pH6.0
UNSPSC code: 12352203

E-Cadherin is a transmembrane glycoprotein, plays an important role in epithelial cell adhesion. A decreased expression of E-Cadherin is associated with metastatic potential and poor prognosis in breast cancer and esophagus cancer. In combination with p120 Catenin or Cytokeratin, it is useful for the differentiation between ductal (E-Cadherin positive) and lobular (E-Cadherin negative) breast carcinomas. It may also help in diagnosis of mesothelioma. (Shipping Cost: €200.00)

Cadherin-E/CD324 [EP6]

E-Cadherin is a transmembrane glycoprotein, plays an important role in epithelial cell adhesion. A decreased expression of E-Cadherin is associated with metastatic potential and poor prognosis in breast cancer and esophagus cancer. In combination with p120 Catenin or Cytokeratin, it is useful for the differentiation between ductal (E-Cadherin positive) and lobular (E-Cadherin negative) breast carcinomas. It may also help in diagnosis of mesothelioma.