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Brachyury/Bry/T-Antibody [A4]

Product group: Primary
Monoclonal/ Polyclonal: Monoclonal
Clone: A4
Host: Mouse
Isotype: IgG2b
Application: ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)
Application notes: 25-100
Conjugation Type: Unconjugated
Lightchain type: Kappa
Reactivity: Human, Mouse, Rat
General notes: Localization: nucleus.
Buffer: citrate pH6.0 or EDTA pH8.0
UNSPSC code: 12352203

The protein encoded by this gene is an embryonic nuclear transcription factor that binds to a specific DNA element, the palindromic T-site. It binds through a region in its N-terminus, called the T-box, and effects transcription of genes required for mesoderm formation and differentiation. The protein is localized to notochord-derived cells. Two transcript variants encoding different isoforms have been found for this gene. Involved in the transcriptional regulation of genes required for mesoderm formation and differentiation. Binds to a palindromic site (called T site) and activates gene transcription when bound to such a site. (Shipping Cost: €200.00)

Brachyury/Bry/T-Antibody [A4]

The protein encoded by this gene is an embryonic nuclear transcription factor that binds to a specific DNA element, the palindromic T-site. It binds through a region in its N-terminus, called the T-box, and effects transcription of genes required for mesoderm formation and differentiation. The protein is localized to notochord-derived cells. Two transcript variants encoding different isoforms have been found for this gene. Involved in the transcriptional regulation of genes required for mesoderm formation and differentiation. Binds to a palindromic site (called T site) and activates gene transcription when bound to such a site.