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BLC/BCA-1/CXCL13/B lymphocyte chemoattractant Polyclonal
Product group: | Primary |
Monoclonal/ Polyclonal: | Polyclonal |
Host: | Rabbit |
Isotype: | IgG |
Application: | Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC) |
Application notes: | Prediluted |
Conjugation Type: | Unconjugated |
Reactivity: | Human, Dog |
General notes: | Localization: secreted. |
Buffer: | citrate pH6.0 or EDTA pH8.0 |
UNSPSC code: | 12352203 |
Burkitt’s lymphoma receptor 1 (Blr1) is a lymphocyte specific chemokine receptor expressed at low levels in secondary lymphoid tissues and in defined structures of the cerebellum. The G protein-coupled receptor has significant homology to other chemokine receptors. Stimulation of Blr1 by its ligand, B lymphocyte chemo-attractant (BLC) results in an influx of calcium into the cell and the chemotaxis of the cell. Blr1 is required for B cell migration into splenic and Peyer’s patch follicles. BLC expression in Peyer’s patches is highest in germinal centers, where B cells undergo somatic mutation and affinity maturation. (Shipping Cost: €200.00)
BLC/BCA-1/CXCL13/B lymphocyte chemoattractant Polyclonal
Burkitt’s lymphoma receptor 1 (Blr1) is a lymphocyte specific chemokine receptor expressed at low levels in secondary lymphoid tissues and in defined structures of the cerebellum. The G protein-coupled receptor has significant homology to other chemokine receptors. Stimulation of Blr1 by its ligand, B lymphocyte chemo-attractant (BLC) results in an influx of calcium into the cell and the chemotaxis of the cell. Blr1 is required for B cell migration into splenic and Peyer’s patch follicles. BLC expression in Peyer’s patches is highest in germinal centers, where B cells undergo somatic mutation and affinity maturation.
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