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Adipophilin/ADFP/PLIN2 [ADFP/1493]

Product group: Primary
Monoclonal/ Polyclonal: Monoclonal
Clone: ADFP/1493
Host: Mouse
Isotype: IgG2b
Application: ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)
Application notes: 50-200
Conjugation Type: Unconjugated
Lightchain type: Lambda
Reactivity: Human
General notes: Localization: cytoplasm. Membrane.
Buffer: citrate pH6.0
UNSPSC code: 12352203

Recognizes a protein of 48kDa, which is identified as Adipophilin. It belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue. However, it is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases. (Shipping Cost: €200.00)

Adipophilin/ADFP/PLIN2 [ADFP/1493]

Recognizes a protein of 48kDa, which is identified as Adipophilin. It belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue. However, it is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases.