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ALDH1A1 (Aldehyde Dehydrogenase 1A1) [44]
Description ALDH1A1 belongs to the aldehyde dehydrogenase family. Aldehyde dehydrogenase is the next enzyme after alcohol dehydrogenase in the major pathway of alcohol metabolism. ALDH1A1 is known to catalyze the oxidation of retinaldehyde to retinoic acid. ALDH1A1 has been a well established marker of hematopoietic stem cells and progenitor cells. Recent studies also show that ALDH1A1 is an important cancer stem marker associated with tumor progression in cancers of the breast, prostate and lung. This antibody labels epithelial cells of the stomach, liver, kidney and thyroid, neural cells and stromal cells including endothelial cells. In tumors, it stains stromal cells as well as tumor cells in many types of cancers. (Shipping Cost: €200.00) Host Mouse Application Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human 
1 ml more info 
14 days 
€361,40 Add to cart -
ALDH1A1 (Aldehyde Dehydrogenase 1A1) [44]
Description ALDH1A1 belongs to the aldehyde dehydrogenase family. Aldehyde dehydrogenase is the next enzyme after alcohol dehydrogenase in the major pathway of alcohol metabolism. ALDH1A1 is known to catalyze the oxidation of retinaldehyde to retinoic acid. ALDH1A1 has been a well established marker of hematopoietic stem cells and progenitor cells. Recent studies also show that ALDH1A1 is an important cancer stem marker associated with tumor progression in cancers of the breast, prostate and lung. This antibody labels epithelial cells of the stomach, liver, kidney and thyroid, neural cells and stromal cells including endothelial cells. In tumors, it stains stromal cells as well as tumor cells in many types of cancers. (Shipping Cost: €200.00) Host Mouse Application Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human
7 ml more info 14 days
€187,20 Add to cart -
ALDH1A1 (Aldehyde Dehydrogenase 1A1) [ALDH1A1/1381]
Description ALDH1A1 belongs to the ALDH enzymes, a family of evolutionarily conserved enzymes comprised of 19 isoforms that are localized in the cytoplasm, mitochondria or nucleus. ALDH1A1 is predominantly expressed in the epithelium of testis, brain, eye, liver, kidney, as well as neural and hematopoietic stem cells. Reportedly, high ALDH1A1 expression is found in solitary fibrous tumor (SFT) and hemangiopericytoma (HPC), compared to meningiomas and synovial sarcomas. In combination with CD34, ALDH1A1 may be useful for the differentiation among SFT, HPC, meningioma, and synovial sarcoma. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human
1 ml more info 14 days
€361,40 Add to cart -
ALDH1A1 (Aldehyde Dehydrogenase 1A1) [ALDH1A1/1381]
Description ALDH1A1 belongs to the ALDH enzymes, a family of evolutionarily conserved enzymes comprised of 19 isoforms that are localized in the cytoplasm, mitochondria or nucleus. ALDH1A1 is predominantly expressed in the epithelium of testis, brain, eye, liver, kidney, as well as neural and hematopoietic stem cells. Reportedly, high ALDH1A1 expression is found in solitary fibrous tumor (SFT) and hemangiopericytoma (HPC), compared to meningiomas and synovial sarcomas. In combination with CD34, ALDH1A1 may be useful for the differentiation among SFT, HPC, meningioma, and synovial sarcoma. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human
7 ml more info 14 days
€187,20 Add to cart -
Alkaline Phosphatase (Intestinal) [V17.1]
Description Alkaline phosphatase, germ cell; Alkaline phosphatase, testicular and thymus; Akp2; Alkaline phosphatase intestinal; Alkaline phosphatase liver/bone/kidney; Alkaline phosphatase placental; Alkaline phosphatase placental like 2; Alkaline phosphatase, tissue-nonspecific; ALPG; ALPI; ALPL; ALPP; ALPPL; ALPPL2; AP TNAP; Germ cell alkaline phosphatase; HOPS; Intestinal alkaline phosphatase (IAP); Kasahara isozyme; Nagao isozyme; PLAP; PLAP like; Regan isozyme; Testicular and thymus alkaline phosphatase; Tissue non-specific alkaline phosphatase; Tissue nonspecific ALP (TNAP or TNSALP) (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC) (Frozen) Reactivity Human, Bovine
1 ml more info 14 days
€361,40 Add to cart -
Alkaline Phosphatase (Intestinal) [V17.1]
Description Alkaline phosphatase, germ cell; Alkaline phosphatase, testicular and thymus; Akp2; Alkaline phosphatase intestinal; Alkaline phosphatase liver/bone/kidney; Alkaline phosphatase placental; Alkaline phosphatase placental like 2; Alkaline phosphatase, tissue-nonspecific; ALPG; ALPI; ALPL; ALPP; ALPPL; ALPPL2; AP TNAP; Germ cell alkaline phosphatase; HOPS; Intestinal alkaline phosphatase (IAP); Kasahara isozyme; Nagao isozyme; PLAP; PLAP like; Regan isozyme; Testicular and thymus alkaline phosphatase; Tissue non-specific alkaline phosphatase; Tissue nonspecific ALP (TNAP or TNSALP) (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC) (Frozen) Reactivity Human, Bovine
7 ml more info 14 days
€187,20 Add to cart -
Alkaline Phosphatase (Placental)/PLAP [ALP/870]
Description Reacts with a 70kDa membrane-bound isozyme (Regan and Nagao type) of Placental Alkaline Phosphatase (PLAP) occurring in the placenta during the 3rd trimester of gestation. It is highly specific for PLAP and shows no cross-reaction with other isozymes of alkaline phosphatase. Anti-PLAP reacts with germ cell tumors and can discriminate between these and other neoplasms. Somatic neoplasms e.g. breast, gastrointestinal, prostatic, and urinary cancers may also immunoreact with antibodies to PLAP. Anti-PLAP positivity in conjunction with anti-keratin negativity favors seminoma over carcinoma. Germ cell tumors are usually anti-keratin positive, but they regularly fail to stain with anti-EMA, whereas most carcinomas stain with anti-EMA. Anti-PLAP has been useful in the diagnosis of gestational trophoblastic disease. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human
1 ml more info 14 days
€361,40 Add to cart -
Alkaline Phosphatase (Placental)/PLAP [ALP/870]
Description Reacts with a 70kDa membrane-bound isozyme (Regan and Nagao type) of Placental Alkaline Phosphatase (PLAP) occurring in the placenta during the 3rd trimester of gestation. It is highly specific for PLAP and shows no cross-reaction with other isozymes of alkaline phosphatase. Anti-PLAP reacts with germ cell tumors and can discriminate between these and other neoplasms. Somatic neoplasms e.g. breast, gastrointestinal, prostatic, and urinary cancers may also immunoreact with antibodies to PLAP. Anti-PLAP positivity in conjunction with anti-keratin negativity favors seminoma over carcinoma. Germ cell tumors are usually anti-keratin positive, but they regularly fail to stain with anti-EMA, whereas most carcinomas stain with anti-EMA. Anti-PLAP has been useful in the diagnosis of gestational trophoblastic disease. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human
7 ml more info 14 days
€187,20 Add to cart -
Alkaline Phosphatase (tissue-nonspecific) [ALAP/597]
Description There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization; however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to hypo-phosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of this disorder can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms. Alternatively sp Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human, Bovine
1 ml more info 14 days
€361,40 Add to cart -
Alkaline Phosphatase (tissue-nonspecific) [ALAP/597]
Description There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization; however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to hypo-phosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of this disorder can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms. Alternatively sp Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human, Bovine
7 ml more info 14 days
€187,20 Add to cart
